Laboratory Consultation & Collaboration
Comprehensive consulting services for lab build-outs and automation, and subject matter expertise in neurodegeneration, circuit mapping, microscopy, gene therapy, and experimental design.
Areas of Expertise
Neurodegeneration
Deep understanding of neurodegenerative disease mechanisms including ALS, Parkinson's, and Alzheimer's disease. Experience with tau pathology, protein aggregation, and aging research.
Neural Circuit Mapping
Expertise in viral tracing, optogenetics, chemogenetics, and electrophysiology for dissecting neural circuits. Experience with adult neurogenesis and circuit integration.
Gene Therapy & Editing
Comprehensive expertise in AAV and LNP delivery systems, CNS targeting strategies, and CRISPR/engineered nuclease systems. Experience with in vivo and in vitro genome editing, biodistribution analysis, efficacy assessment, and editing optimization. Multiple patents in gene editing.
High-Throughput Screening
Extensive experience designing and executing high-throughput screening campaigns using automated liquid handling systems. Expertise with diverse cellular models including primary cells, cell lines, and 3D organoid systems for drug discovery, genetic screens, and phenotypic assays.
Advanced Microscopy
Expert-level knowledge of tissue clearing, confocal, two-photon, and light-sheet microscopy. Custom optical systems and microscope modifications.
Molecular Biology
Molecular cloning, viral packaging (AAV, lentivirus), RNA-seq (bulk and single-cell), qPCR, immunoblotting, and other core molecular techniques.
Lab Build-Outs & Automation
Consulting on laboratory design, equipment selection, and process automation:
Lab Design
Space planning, workflow optimization, and equipment layout for new or renovated laboratories. Safety considerations and regulatory compliance.
Equipment Selection
Vendor evaluation, specification development, and cost-benefit analysis for microscopes, sequencers, and other major equipment purchases.
Process Automation
Implementation of liquid handlers, plate readers, and custom automation solutions for high-throughput workflows and improved reproducibility.
Custom Tools
Design and fabrication of custom laboratory equipment, from stereotactic rigs to specialized imaging chambers and experimental setups.
Experimental Design & Project Management
Study Design
Develop rigorous experimental designs with appropriate controls, statistical power analysis, and reproducibility considerations.
- Hypothesis development and testing
- Control group selection
- Sample size calculations
- Randomization and blinding strategies
Project Execution
Support throughout the project lifecycle from planning to publication, including troubleshooting, optimization, and team training.
- Protocol optimization
- Troubleshooting and problem-solving
- Team training and mentorship
- Data interpretation and analysis
Collaboration Models
Flexible engagement options to match your project needs:
Consulting
Hourly or project-based consulting for specific technical questions, protocol development, or strategic planning.
Collaboration
Joint research projects with shared intellectual contributions, co-authorship, and mutual benefit.
Training
Hands-on training workshops for your team on specific techniques, equipment, or analysis methods.
Track Record of Success
Ready to Collaborate?
Contact me to discuss how we can work together to advance your research goals.
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